Molecular determinants of Neu5Ac binding to a tripartite ATP independent periplasmic (TRAP) transporter
Sialic acids are nine-carbon amino sugars common on the surface of mammalian cells and on secreted molecules. N-Acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc) are the most prevalent forms in humans (Lewis and Lewis, 2012). A dynamic …